Dr. Shanti Swaroop Srivastava
Principal Investigator
Education & Experiences
- Assistant Professor
- Department of Biological Sciences, Indian Institute of Science Education and Research (IISER), Berhampur, India
- Postdoctoral Fellow (2019-2022)
- Faculty of Medicine, University of British Columbia (UBC), Vancouver, Canada
- Postdoctoral Visiting Fellow (2018-2019)
- National Cancer Institute (NCI), National Institutes of Health (NIH), USA
- Post-Ph.D. work (2016-2018)
- CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India
- Ph.D. (2016)
- CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India
- M.Sc. (2007)
- Jawaharlal Nehru University, New Delhi, India
Biography
Dr. Shanti Swaroop Srivastava is a structural biologist who specializes in cryo-electron microscopy (cryo-EM) and X-ray crystallography. He earned his Ph.D. in structural biology and biophysics from the Centre for Cellular and Molecular Biology (CCMB), Hyderabad. During his Ph.D., Dr. Srivastava elucidated the structures of diverse calcium-binding proteins using X-ray crystallography. Following that, he joined the National Cancer Institute (NCI), NIH, USA and later the University of British Columbia (UBC), Canada for his post-doctoral studies in high-resolution cryo-EM. Dr. Srivastava is enthusiastic about the potential and convenience of single-particle cryo-EM for the investigation of complex and dynamic macromolecular assemblies.
He chose to return to India to establish a research frontier that will focus on resolving biological problems of global concern in human health and disease. In addition, he is passionate about disseminating structural biology knowledge and enjoys training students for creative research.
Awards & Recognition
- Fulbright-Nehru Postdoctoral Research Fellowship (2018-2019): Supplemental Visiting Fellow Award (SVFA) Fellowship, NCI, NIH, USA (2018-2019)
- Ratna Phadke Award: For a young scientist from the Indian Biophysical Society (2017)
- Junior and Senior Research Fellowships: From the Council of Scientific and Industrial Research (CSIR), India
- Scholarship: Department of Biotechnology (D.B.T.), Government of India
- National Scholarship: During Intermediate (10+2)
Research Interest
Molecular interactions control every aspect of cellular function, making it essential to decode protein-protein, protein-nucleic acid, and protein-ligand interactions. Understanding how these interactions are disrupted in various disease conditions is crucial for developing effective therapeutics and drugs. To achieve this, we utilize cryo-electron microscopy (cryo-EM) and X-ray crystallography to determine high-resolution structures of macromolecular complexes.
- Decoding molecular interactions to understand cellular events
- Investigating perturbations in disease conditions
- Utilizing cryo-EM and X-ray crystallography for structural insights